Methylprednisolone Tablets

Product Name:Methylprednisolone Tablets

Ingredient: Methylprednisolone

Indications:

For the treatment of inflammatory and allergic diseases in dogs, or as part of the treatment regimen for such conditions, including allergic or non-specific dermatitis, musculoskeletal disorders, ocular and otic inflammation, and other inflammatory/allergic diseases responsive to glucocorticoid therapy (e.g., immune-mediated diseases).

Description:

This product is in the form of pink tablets (2mg dosage) or white tablets (4mg dosage).

Pharmacology：

Pharmacodynamics：

A synthetic glucocorticoid with pharmacological effects similar to hydrocortisone. Methylation at carbon 6 of the tetracyclic structure increases anti-inflammatory potency by 5‑fold compared with hydrocortisone and eliminates mineralocorticoid activity.

Drug Interactions：

1. Concomitant use with barbiturates, phenylbutazone, phenytoin, or rifampicin may accelerate metabolism and reduce the effects of glucocorticoids.

2. Glucocorticoids may reduce the response to anticoagulants.

Key Advantages:

1.High anti-inflammatory potency.

2.Rapid oral absorption.

3.Good safety profile at recommended doses.

4.Flexible dosing for acute & chronic conditions.

Dosage and Administration

For oral use. The initial daily dose should be divided into 2 equal administrations.

Adverse Reactions:

1.During the treatment process, glucocorticoid drugs may cause significant changes in fat, carbohydrate, protein and mineral metabolism, such as redistribution of body fat, muscle weakness and osteoporosis. The effective dose during treatment will inhibit the hypothalamic-pituitary-adrenal axis.

2.May lead to adrenal insufficiency or atrophy after withdrawal.

3.Polyuria, polydipsia, polyphagia; sodium and water retention, hypokalemia with long-term use.

4.Systemic glucocorticoids may cause cutaneous calcinosis.

5.Glucocorticoids are immunosuppressive and may delay wound healing, reduce resistance to existing infections or exacerbate infections.

6.May cause gastrointestinal ulceration, hepatomegaly, elevated liver enzymes.

Precautions:

1.Not recommended for use in pregnant dogs. Laboratory animal data indicate teratogenicity in early pregnancy and risk of premature birth or abortion in late pregnancy.

2.Systemic glucocorticoid therapy is generally contraindicated in dogs with renal disease or diabetes mellitus.

3.In bacterial infections, glucocorticoids should only be used concurrently with appropriate antimicrobial therapy.

4.Do not use in dogs with viral infections.

5.Do not discontinue prolonged therapy abruptly; the dose must be gradually reduced before withdrawal.

Specification:

(1) 2 mg (2) 4 mg

Storage:

Store below 25 ℃, protected from light, in a tightly sealed container.

Shelf Life：

24 months.