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Granisetron Tablets

For canine osteoarthritis pain & inflammation control.

Product Name:Granisetron Tablets

Ingredient: Granisetron

Indications:

For the control of pain and inflammation associated with osteoarthritis in dogs.

Description:

Yellowish-brown to brown, biconvex, oval tablets with speckles.

Pharmacology:

Grapiprant is a non-cyclooxygenase (COX)-inhibiting nonsteroidal anti-inflammatory drug (NSAID) and an antagonist of the prostaglandin E2(PGE2) EP4 receptor.The EP4 receptor is a key receptor responsible for mediating PGE2-induced inflammation and pain, and is a major mediator of nociception.Grapiprant exerts anti-inflammatory and analgesic effects by binding to the EP4 receptor of PGE2.

Key Advantages:

1.Unique Mechanism of Action with Higher Safety.

2.Clear and Targeted Analgesic and Anti-inflammatory Effects.

3.Excellent Pharmacokinetic Characteristics and Convenient Administration.

4.Good Tolerability and Mild Adverse Reactions.

5.Extensive Metabolic Pathways and Low Risk of Drug Interactions.

Dosage and Administration

For oral administration: 2 mg per kg body weight, once daily in dogs.

Body Weight (kg)Strength (mg)Dose (tablets)
3.6~6.8200.5
6.9~13.6201
13.7~20.4600.5
20.5~34601
34.1~681001
>68Appropriate strengths and half-tablets to achieve recommended dose.

Adverse Reactions:

Common adverse reactions in dogs include vomiting, soft feces, diarrhea, and decreased appetite.

Precautions:

1.Halved tablets should be stored in the original packaging.

2.Safety has not been evaluated in dogs younger than 9 months or <3.6 kg. Use as directed by a veterinarian.

3.Safety has not been evaluated in pregnant, lactating, or breeding dogs. Use as directed by a veterinarian.

4.Safety has not been evaluated in dogs with cardiac disease. Use as directed by a veterinarian.

Specification:

(1) 20 mg (2) 60 mg (3) 100 mg

Storage:

Store below 30 ℃.

Shelf Life:

36 months.

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