Dexmedetomidine Hydrochloride Injection

Product Name:Dexmedetomidine Hydrochloride Injection

Ingredient: Dexmedetomidine Hydrochloride

Indications:It is used for calming and pain relief in dogs and cats, facilitating clinical examinations, treatments, small-scale dental surgeries and other minor operations.

It can also be used as an anesthetic pre-medication before general anesthesia for dogs.

Description:This product is a colorless and clear liquid.

Pharmacology：

Dexmedetomidine is a highly selective α₂-adrenergic receptor agonist.It produces sedation, analgesia, anxiolysis and sympatholytic effects by stimulating central α₂-receptors.It has minimal effects on respiratory function, and sedation is characterized by a natural sleep-like state with easy arousal.The onset is rapid, and the duration is short.The sedative and analgesic effects can be rapidly and completely reversed by atipamezole.

Key Advantages:

Fast onset of action and short duration, the best sedative and analgesic effect can be achieved 15-30 minutes after injection, suitable for minor clinical operations and examinations.

Dosage and Administration

Route: Intramuscular injection (IM) / Intravenous injection (IV)

Adverse Reactions:

1.Transient hypertension occurs after administration, followed by blood pressure returning to normal or slightly lower levels.

2.Reduced respiratory rate and hypothermia (the severity is dose-dependent).

3.Slowed gastrointestinal peristalsis, elevated blood glucose and increased urine output due to inhibited insulin release.

4.Spontaneous muscle twitches may occur in dogs after sedation; central nervous stimulation and vomiting may be seen in cats.

5.Potential allergic reactions and paradoxical excitatory responses may occur occasionally.

Precautions:

1.Fast dogs/cats for 12 hours before administration.

2.μg/kg dosage decreases with increased body weight.

3.Contraindicated in animals with organ insufficiency, shock, severe weakness or stress.

4.Handle sedated animals with caution to avoid aggressive behavior.

Specification:

10 ml : 1 mg (Concentration: 0.1 mg/ml)

Storage:

Store in the dark at 15~30℃.

Shelf Life：

36 month; Use within 28 days after opening.