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Clindamycin Hydrochloride Oral Solution

For treatment of canine staphylococcal skin diseases.

Product Name:Clindamycin Hydrochloride Oral Solution

Ingredient: Clindamycin Hydrochloride(C18H33CIN2O5S)

Indications:

For the treatment of canine skin diseases caused by Staphylococcus aureus and Staphylococcus pseudintermedius.

Description:

This product is a colorless to pale yellow clear liquid.

Pharmacology:

This product belongs to the lincosamide class of antibiotics.Clindamycin is an inhibitor of intracellular bacterial protein synthesis,which binds to the 50S subunit of bacterial ribosomes,and may bind to the soluble RNA of some ribosomes,thereby inhibiting the binding of amino acids to these ribosomes,causing irreversible modification of subcellular elements involved in protein synthesis at the bacterial ribosome level.

Key Advantages:

1.Strong Antibacterial Activity & Targeted Efficacy.It has potent effects on major pathogenic bacteria of canine skin diseases, inhibiting bacterial protein synthesis for rapid anti-infection.

2.Excellent Oral Absorption & Stable Pharmacokinetics.It is completely absorbed orally without being affected by food. For dogs, the blood drug concentration peaks quickly (about 1 hour) and is stable, ensuring continuous therapeutic effect.

3.High Safety & Few Adverse Reactions.No obvious adverse reactions when used at the recommended dosage, with good tolerance in dogs, suitable for short-term or long-term (up to 28 days) use.

4.Good Stability & Convenient Storage.

Dosage and Administration

11 mg per kg body weight in dogs (equivalent to 0.44 mL of this product),once daily, for a maximum of 28 consecutive days.

Adverse Reactions:

No adverse reactions have been observed when used at the recommended dosage and administration.

Precautions:

1. Do not use in dogs with a history of hypersensitivity to the active ingredient clindamycin hydrochloride or any of the excipients.

2. Do not use in rabbits, hamsters, guinea pigs, horses or ruminants due to potential gastrointestinal reactions.

3. During long-term treatment (one month or longer), periodic liver and kidney function tests and blood cell counts should be performed.

4. Use with caution in dogs with severe renal disease or hepatic disease accompanied by severe metabolic disorders,and monitor serum clindamycin levels during high-dose treatment.

5. Safety in pregnant and breeding dogs has not been established.

Specification:2.5%, calculated as C18H33CIN2O5S

Storage:

Store below 25 ℃, tightly sealed.

Shelf Life:

24 months; shelf life after first opening is 28 days.

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