Hypericum Perforatum Extract

Hypericum perforatum extract, rich in

 bioactive compounds like hypericin,

hyperforin, and flavonoids, has gained

significant traction in animal husbandry and aquaculture due to its natural anti-inflammatory, antioxidant, and immunomodulatory properties.

1. Health Functions by Animal Category

1.1 Poultry (Chickens, Ducks, Turkeys, Broilers, Layers)

HPE addresses core challenges in poultry farming such as stress, gut disorders, and reduced productivity, with zero residue concerns ideal for export-oriented operations:

Gut Health Regulation: 

Inhibits pathogenic bacteria (e.g., E. coli, Salmonella) and reduces intestinal inflammation via suppressing pro-inflammatory cytokines (TNF-α, IL-6). It alleviates diarrhea and enteritis caused by feed changes, crowding, or mycotoxin exposure, improving feed conversion ratio (FCR).

Stress Resistance Enhancement:

Mitigates oxidative stress from transport, vaccination, or temperature fluctuations by boosting antioxidant enzyme activity (SOD, GSH-Px) in the liver and serum. Reduces stress-induced weight loss in broilers and egg drop in layers.

Immunomodulation:

Stimulates lymphocyte proliferation and antibody production, enhancing immunity against common poultry diseases (e.g., Newcastle disease, infectious bronchitis) and reducing antibiotic dependency.

Egg Quality Improvement: 

Increases eggshell thickness and reduces cholesterol content in egg yolks (via flavonoid antioxidants), adding value to premium egg products for global markets.

1.2 Livestock (Cattle, Sheep, Goats)

For livestock, HPE focuses on liver protection, reproductive health, and musculoskeletal wellness, aligning with organic and sustainable farming trends overseas:

Liver Detoxification:

Shields hepatocytes from damage caused by mycotoxins (aflatoxins, zearalenone) in feed and metabolic toxins. Reduces elevated liver enzyme levels (ALT, AST) in cattle , maintaining optimal liver function.

Anti-Inflammatory & Analgesic Effects:

Relieves joint inflammation in dairy cows with osteoarthritis and reduces post-surgical pain in pigs. Improves mobility in breeding livestock, enhancing reproductive performance.

Reproductive Health Support: 

Enhances sperm motility and viability in boars and rams; reduces postpartum uterine inflammation in sows and cows, shortening the inter-calving interval.

Gastrointestinal Protection:

Reduces ruminal inflammation in cattle, improving nutrient absorption and weight gain rates.

1.3 Aquaculture (Fish, Shrimp, Crab)

HPE is a natural alternative to synthetic additives in aquaculture, addressing stress, disease, and poor survival rates in intensive farming systems:

Anti-Stress & Survival Rate Boost:

Mitigates oxidative stress in fish (e.g., tilapia, salmon) during transport, hypoxia, or water quality fluctuations. Improves survival rates of shrimp larvae and post-larvae by 15–20% in high-density ponds.

Disease Resistance:

Enhances non-specific immunity in aquatic organisms by increasing phagocytic activity of macrophages and lysozyme levels. Reduces mortality caused by bacterial infections (e.g., Aeromonas hydrophila in fish, Vibrio parahaemolyticus in shrimp).

Skin & Mucus Barrier Enhancement:

Accelerates wound healing in fish injured by netting or fighting. Strengthens the mucus barrier, reducing pathogen adhesion to the skin and gills.

Growth Promotion:

Improves feed intake and FCR in commercial fish species (e.g., carp, catfish) by regulating gut microflora balance and nutrient metabolism.

2. Clinical Trials

3.Dosage

3.1 Poultry (Oral Administration via Feed/Water)

3.2 Livestock

3.3 Aquaculture

4. Key Export & Safety Notes

Residue & Regulation Compliance: HPE is classified as a natural plant extract in most countries (EU, US, Southeast Asia), with no maximum residue limits (MRLs) for food-producing animals—facilitating cross-border trade.