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Enramycin Premix

Ingredient: Enramycin Premix 4% Mechanism of Action: Inhibits bacterial cell wall synthesis, leading to the death of susceptible Gram-positive bacteria….

Ingredient: Enramycin Premix 4%

Mechanism of Action:

Inhibits bacterial cell wall synthesis, leading to the death of susceptible Gram-positive bacteria.

Key Target Pathogens:

Primarily Clostridium perfringens (the main cause of necrotic enteritis), Staphylococcus spp., Streptococcus spp., and some drug-resistant Gram-positive bacteria. It has minimal activity against Gram-negative bacteria and no cross-resistance with other common veterinary antibiotics (e.g., penicillins, macrolides), making it valuable for managing resistant infections.

Pharmacokinetic Advantage:

Poorly absorbed from the gastrointestinal tract (GIT) in animals. This means it remains concentrated in the intestinal lumen, targeting gut pathogens while minimizing systemic exposure (reducing residue risks and systemic side effects).

Indications

Enramycin 4% Premix is primarily indicated for swine and poultry (broilers, turkeys) to prevent/treat intestinal bacterial infections and enhance production performance. Its GIT-localized action makes it especially effective for gut health management.

Animal SpeciesPrimary Indications
SwinePrevention & Treatment of Intestinal Diseases

Necrotic enteritis

Caused by Clostridium perfringens (common in weaned piglets and growing pigs, characterized by diarrhea, intestinal necrosis, and high mortality).

Bacterial diarrhea

Associated with sensitive Gram-positive pathogens (e.g., Staphylococcus aureus) in suckling and weaned piglets.

Post-weaning gut health maintenance: Reduces subclinical intestinal infections to improve gut barrier function.

Growth Promotion

Enhances feed conversion rate (FCR) and average daily gain (ADG) in weaned piglets, growing-finishing pigs, and suckling piglets (via reducing gut inflammation and nutrient loss from infections).

Animal SpeciesPrimary Indications
PoultryPrevention & Treatment of Intestinal Diseases

Necrotic enteritis

A major disease in broilers and turkeys caused by Clostridium perfringens, which leads to reduced weight gain, increased mortality, and poor feed efficiency.

Clostridial enteritis

Subclinical or clinical infections that disrupt gut health and nutrient absorption.

Growth Promotion

Improves weight gain and FCR in broilers (from day-old chicks to slaughter) and turkeys by maintaining a healthy intestinal microflora and reducing pathogen-induced gut damage. |

Dosage

Animal SpeciesPurposeDosage (Enramycin 4% Premix per 1000 kg of Complete Feed)Active Enramycin Equivalent (per kg of Feed)Duration of Use
SwineGrowth Promotion– Weaned piglets: 100–200 g- Growing-finishing pigs: 50–100 g- Suckling piglets (via sow feed): 150–250 g (administered to sows to protect piglets via milk transfer)4–8 mg/kg2–4 mg/kg6–10 mg/kgContinuous use from weaning until slaughter (or up to the withdrawal period).
SwineTreatment of Necrotic Enteritis/Diarrhea200–400 g8–16 mg/kg7–14 days. Discontinue if no clinical improvement is seen after 3–5 days (consult a veterinarian for re-diagnosis).
PoultryGrowth Promotion (Broilers/Turkeys)50–100 g2–4 mg/kgContinuous use from day-old chicks to slaughter (or up to the withdrawal period).
PoultryTreatment of Necrotic Enteritis100–200 g4–8 mg/kg5–7 days. Extend only if recommended by a licensed veterinarian.

Withdrawal Period

Swine: 7–10 days (slaughter).

Poultry (broilers/turkeys): 3–7 days (slaughter); 

Storage: Keep in a dry and cool place not exceeding 30℃ and avoid light.

Packing: 25kg/bag

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