Bacitracin Zinc Premix

Ingredient: Bacitracin Zinc 15%Core IndicationsPrevention and Control of Gram-Positive Bacterial Infections Animal Category Target Infections & Pathogens Clinical Scenario &…

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Ingredient: Bacitracin Zinc 15%
Core Indications
Prevention and Control of Gram-Positive Bacterial Infections

Animal Category	Target Infections & Pathogens	Clinical Scenario & Benefit
Poultry (Broilers, Turkey Poults)	– Necrotic Enteritis (NE): Caused by Clostridium perfringens (Type A/C)- Omphalitis (Navel Infection): Caused by Staphylococcus aureus, Streptococcus spp.- Bacterial Dermatitis: Caused by Staphylococcus spp.	– Prevents NE (severe intestinal necrosis, 10–50% mortality in broilers) and reduces outbreak severity.- Lowers early chick/poult mortality (1–7 days old) from navel infections.- Minimizes skin defects (e.g., hock burn) in broilers, improving carcass quality.
Swine (Weaned Piglets, Grow-Finish Pigs)	– Post-Weaning Diarrhea (PWD): Targets Clostridium perfringens (Type C) (co-pathogen with E. coli)- Mild Porcine Dysentery: Adjunct control of Brachyspira hyodysenteriae (with other antibiotics)	– Reduces PWD-related growth stunting by suppressing gram-positive bacteria that worsen intestinal damage.- Supports recovery from mild dysentery by limiting secondary gram-positive infections.
Cattle (Beef Calves, Pre-Lactating Dairy Calves)	– Calf Diphtheria: Caused by Fusobacterium necrophorum, Staphylococcus spp.- Calf Enteritis: Caused by Clostridium perfringens (Type C)	– Prevents/treats oral ulcers and throat inflammation in 1–3-month-old calves, reducing appetite loss and pneumonia risk.- Controls clostridial enteritis in intensive calf rearing systems.

Growth Promotion

By inhibiting harmful gram-positive bacteria in the gut, Bacitracin Zinc 15% Premix reduces subclinical inflammation and nutrient competition, improving feed conversion efficiency (FCE) (more weight gain per kg of feed) and average daily gain (ADG).

Growth Performance & Feed Efficiency

Broilers:

Supplementation at 11–55 mg/kg (equivalent to 0.73–3.67 g/ton of 15% premix) improves feed conversion ratio (FCR) by 2.5–4.7% and daily weight gain by 2.5–7% compared to control groups.

Higher doses (e.g., 550 mg/kg) may not enhance growth further but can reduce relative deep pectoral muscle development.

Laying Hens:

At 10–50 mg/kg (0.67–3.33 g/ton of 15% premix), bacitracin zinc increases egg production by 4–7%, egg weight by 4.8%, and shell strength by 6%.

It also mitigates the negative impact of heat stress, improving feed intake and egg quality during hot weather.

This is approved for:

Broilers: Shortens production cycles and improves flock uniformity.

Weaned Piglets: Mitigates post-weaning growth checks.

Beef Calves: Supports early growth for efficient fattening later.

Target Species & Prohibited Uses

Approved Species (Age-Specific)

Species	Approved Age/Production Stage
Poultry	Broilers (0–42 days), turkey poults (0–12 weeks), growing ducks (0–6 weeks)
Swine	Weaned piglets (3–8 weeks), grow-finish pigs (8 weeks to slaughter)
Cattle	Beef calves (1–6 months), pre-lactating dairy calves (1–3 months; stop 30 days before calving)

Prohibited Uses (Critical!)

Egg-laying hens (layers): Bacitracin zinc accumulates in eggs, exceeding food safety residue limits.

Lactating dairy cows: Residues transfer to milk; only for pre-lactating calves.

Breeding animals (sows, boars, breeding cattle): No growth/infection benefit; unnecessary residue risk.

Companion animals (dogs, cats): Not approved—use pet-specific bacitracin formulations.

Dosage

Poultry

Poultry Type/Stage	Purpose	Bacitracin Zinc 15% Premix per Ton of Feed	Active Bacitracin Zinc Concentration	Duration of Use
Broilers (0–42 days)	Growth Promotion + NE Prevention	400–600 g	60–90 mg/kg feed	Full grow-out period (stop 5 days before slaughter).
Broilers	NE Treatment (Outbreak)	800–1,200 g	120–180 mg/kg feed	5–7 days; reduce to prevention dose if symptoms resolve.
Turkey Poults (0–12 weeks)	Growth Promotion + Infection Prevention	500–700 g	75–105 mg/kg feed	Until 12 weeks of age (stop 7 days before slaughter).
Growing Ducks (0–6 weeks)	Growth Promotion + Gut Health	400–500 g	60–75 mg/kg feed	Full growing period (stop 5 days before slaughter).

Swine

Swine Stage	Purpose	Bacitracin Zinc 15% Premix per Ton of Feed	Active Bacitracin Zinc Concentration	Duration of Use
Weaned Piglets (3–8 weeks)	Growth Promotion + PWD Prevention	600–800 g	90–120 mg/kg feed	2–4 weeks post-weaning.
Weaned Piglets	PWD Treatment (Adjunct)	1,000–1,200 g	150–180 mg/kg feed	5–7 days (use with E. coli-targeted antibiotics).
Grow-Finish Pigs (8 weeks to slaughter)	Growth Promotion	300–500 g	45–75 mg/kg feed	Full fattening period (stop 3 days before slaughter).

Cattle

Cattle Type/Stage	Purpose	Bacitracin Zinc 15% Premix per Ton of Feed	Active Bacitracin Zinc Concentration	Duration of Use
Beef Calves (1–6 months)	Growth Promotion + Enteritis Prevention	500–700 g	75–105 mg/kg feed	4–6 weeks (start at 1 month old).
Pre-Lactating Dairy Calves (1–3 months)	Calf Diphtheria Prevention	600–800 g	90–120 mg/kg feed	Until 3 months old (stop 30 days before calving).
Beef Calves	Calf Enteritis Treatment	800–1,000 g	120–150 mg/kg feed	5–7 days.

Withdrawal Period

Animal Species	Withdrawal Period for Meat	Withdrawal Period for Milk (Dairy Cattle)
Broilers	5 days	N/A
Turkeys	7 days	N/A
Swine	3 days	N/A
Beef Calves	7 days	N/A
Pre-Lactating Dairy Calves	7 days	30 days (stop 30 days before calving)

Storage: Keep in a dry and cool place not exceeding 30℃ and avoid light.

Packing: 25kg/bag

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Bacitracin Zinc Premix

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